Saito M, Tomonaga M, Narabayashi H
J Neurol. 1978 Dec 22;219(4):261-71. doi: 10.1007/BF00312979.
Pathological changes of the fusimotor endings in parkinsonism, motor neuron disease and myasthenia were examined by the acetylcholinesterase technic on serial sections. In parkinsonism, the diffuse endings, which are thought to be supplied by the static gamma nerve fibers, showed remarkable enlargement, while en plaque and en grappe endings were atrophic. In motor neuron disease, en plaque and en grappe endings, which are thought to be innervated by the beta nerve fibers and dynamic gamma nerve fibers respectively, revealed marked atrophy. However the diffuse endings were normal. In myasthenia gravis and myasthenic syndrome (Eaton-Lambert syndrome), en plaque and en grappe endings were atrophic, though only the diffuse endings were spared. The significance of these changes in the fusimotor endings is discussed.
采用乙酰胆碱酯酶技术对帕金森病、运动神经元病和重症肌无力患者的连续切片中肌梭运动终末的病理变化进行了检查。在帕金森病中，被认为由静态γ神经纤维支配的弥漫性终末显著增大，而板状终末和葡萄状终末萎缩。在运动神经元病中，分别被认为由β神经纤维和动态γ神经纤维支配的板状终末和葡萄状终末显著萎缩。然而，弥漫性终末正常。在重症肌无力和肌无力综合征（伊顿-兰伯特综合征）中，板状终末和葡萄状终末萎缩，尽管只有弥漫性终末幸免。讨论了这些肌梭运动终末变化的意义。
