Shi G, Weh H J, Hossfeld D K
Department of Oncology/Haematology, Medical University Clinic, Hamburg, Germany.
Hematol Oncol. 1993 Mar-Apr;11(2):81-7. doi: 10.1002/hon.2900110205.
Four patients with acute leukemia are presented in whom conventional karyotypic analysis had revealed complex numerical and structural changes including unidentifiable (marker) chromosomes. It is demonstrated that the application of fluorescence in situ hybridization (FISH) may contribute to the identification of such anomalies.
