Suzuki H, Baba S
Department of Dermatology, Surugadai Nihon University Hospital, Tokyo, Japan.
J Dermatol. 1993 Jul;20(7):424-7. doi: 10.1111/j.1346-8138.1993.tb01311.x.
A case of cactus granuloma due to the thorns of Opuntia bieglovii Engelman is reported. A 24-year-old Japanese man contacted the thorns of this cactus in Palm Springs, California, U.S.A., and, three months later, numerous, slightly elevated papules 2 to 4 mm in diameter appeared on the dorsum of his right hand and fingers. Histopathological examination revealed many small granulomas surrounding the bristle fragments throughout the dermis. The granulomas consisted of epithelioid cells, Langhans type and foreign body type giant cells. The fragments of the barbed bristles gave strongly positive reactions with PAS. Two hypothetical mechanisms, one allergic and the other non-allergic, are offered to explain this granuloma formation and are discussed with reference to the literature.
报告了一例由比格洛氏仙人掌（Opuntia bieglovii Engelman）的刺引起的仙人掌肉芽肿病例。一名24岁的日本男子在美国加利福尼亚州棕榈泉接触了这种仙人掌的刺，三个月后，其右手背和手指上出现了许多直径为2至4毫米的略微隆起的丘疹。组织病理学检查显示，整个真皮层中有许多围绕刷毛碎片的小肉芽肿。肉芽肿由上皮样细胞、朗汉斯型和异物型巨细胞组成。带刺刷毛的碎片对PAS呈强阳性反应。本文提出了两种假说机制，一种是过敏机制，另一种是非过敏机制，用以解释这种肉芽肿的形成，并结合文献进行了讨论。
