Koga T, Ishizaki H, Matsumoto T, Hori Y
Department of Dermatology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
J Dermatol. 1993 Jul;20(7):441-3. doi: 10.1111/j.1346-8138.1993.tb01315.x.
Interferon-gamma (IFN-gamma), interleukin 2 (IL-2) and granulocyte/macrophage colony-stimulating factor (GM-CSF) were detected in the culture supernatant after 72 hours incubation with trichophytin in the peripheral blood mononuclear cells (PBMC) obtained from a patient who had a dermatophyte infection. These findings indicate that this patient has peripheral T-lymphocytes that produced IFN-gamma, IL-2 and GM-CSF, which may play roles in the development of delayed-type hypersensitivity (DTH) reaction in the skin.
从一名皮肤癣菌感染患者获取的外周血单个核细胞（PBMC）中，用毛癣菌素孵育72小时后，在培养上清液中检测到γ干扰素（IFN-γ）、白细胞介素2（IL-2）和粒细胞/巨噬细胞集落刺激因子（GM-CSF）。这些发现表明，该患者的外周T淋巴细胞可产生IFN-γ、IL-2和GM-CSF，它们可能在皮肤迟发型超敏反应（DTH）的发生过程中发挥作用。
