Coady M S, Polacarz S, Page R E
Department of Plastic Surgery, Northern General Hospital, Sheffield.
J Hand Surg Br. 1993 Aug;18(4):478-81. doi: 10.1016/0266-7681(93)90151-5.
Malignant peripheral nerve sheath tumours (MPNST) are spindle cell sarcomas normally situated in the deep soft tissues. Cutaneous MPNST is an uncommon variant, usually occurring in the head and neck. When it arises in the upper limb this tumour may pose a considerable diagnostic and therapeutic problem. We present a case of cutaneous MPNST arising in the hand. Tumour extension was exclusively perineural along three major nerve trunks from an interdigital origin. Current knowledge of the clinical behaviour of cutaneous MPNST is reviewed.
恶性外周神经鞘瘤（MPNST）是通常位于深部软组织的梭形细胞肉瘤。皮肤MPNST是一种罕见的变异型，通常发生在头颈部。当它出现在上肢时，这种肿瘤可能会带来相当大的诊断和治疗难题。我们报告一例发生在手部的皮肤MPNST病例。肿瘤从指间起源，沿三条主要神经干呈神经周围蔓延。本文对皮肤MPNST临床行为的现有知识进行了综述。
