Tanaka M, Shimizu H, Monden T, Mori M
First Department of Internal Medicine, Gunma University School of Medicine, Japan.
J Med. 1993;24(2-3):203-8.
We report a case with idiopathic edema accompanied with excessive sweating on bathing. The subject is a 26 year-old male. He was admitted to our hospital because of pretibial edema. He complained of excessive sweating only after daily bathing. Sweating on daily bathing reduced pretibial edema after long-term standing. Daily urine volume decreased by about 200 to 500 mL/day on bathing everyday. Plasma renin, aldosterone and bradykinin levels increased. Subcutaneous injection of pilocarpine increased sweating around the injection site. The cessation of daily bathing restored plasma renin, aldosterone and bradykinin levels; urine volumes increased. However, pretibial edema appeared and body weight increased by 8.5 Kg. Serum triiodothyronine (T3), thyroxine (T4) levels and basal metabolic rate (BMR) decreased. Circulating plasma volume increased with the cessation of bathing. Alterations in the autonomic nervous system may be involved in the appearance of general edema through increased plasma volume due to altered sweating function.
我们报告一例特发性水肿伴有沐浴时多汗的病例。患者为一名26岁男性。他因胫前水肿入院。他仅在每日沐浴后出现多汗症状。每日沐浴时出汗可减轻长期站立后的胫前水肿。每日沐浴时尿量每天减少约200至500毫升。血浆肾素、醛固酮和缓激肽水平升高。皮下注射毛果芸香碱可增加注射部位周围的出汗。停止每日沐浴后,血浆肾素、醛固酮和缓激肽水平恢复正常;尿量增加。然而,胫前水肿出现,体重增加了8.5千克。血清三碘甲状腺原氨酸(T3)、甲状腺素(T4)水平及基础代谢率(BMR)下降。停止沐浴后循环血浆量增加。自主神经系统的改变可能通过出汗功能改变导致血浆量增加,从而引起全身性水肿。