Orr M B, Barlow R M, Ryder M L
Res Vet Sci. 1977 Jan;22(1):56-61.
The structure of the epidermis and dermis, and the distribution of reticulin, glycogen, lipid and sulphydryl groups in the skin have been examined in control and Border disease affected sheep fetuses at 95 and 115 days' gestation. In Border disease, there was a temporary retardation of development of the epidermis and skin follicles at 95 days. There was no difference in the structure of the dermis between control and experimental fetuses at either age. No evidence was found to suggest that the keratogenous process was abnormal in Border disease, but the sulphydryl zone of the primary fibres of affected fetuses was situated nearer the skin surface than in control fetuses. This may have been a consequence of the larger size of primary follices in Border disease. Glycogen present in the undifferentiated epidermis of both groups at 95 days' gestation was absent from the stratified squamous epithelium of the 115 days's fetuses. Glycogen and lipid droplets were present in the outer root sheath of primary follicles of all fetuses examined, but their significance is unknown.
对妊娠95天和115天的对照羊胎儿及患边界病的羊胎儿的表皮和真皮结构，以及网状纤维、糖原、脂质和巯基在皮肤中的分布进行了检查。在边界病中，95天时表皮和皮肤毛囊的发育出现暂时迟缓。在这两个年龄段，对照胎儿和实验胎儿的真皮结构均无差异。未发现证据表明边界病中的角质形成过程异常，但患病胎儿初级纤维的巯基区比对照胎儿更靠近皮肤表面。这可能是边界病中初级毛囊较大的结果。妊娠95天时两组未分化表皮中存在的糖原，在妊娠115天胎儿的复层鳞状上皮中不存在。在所检查的所有胎儿的初级毛囊外根鞘中均存在糖原和脂滴，但其意义尚不清楚。
