Krishnaswamy S, Nesheim M E, Pryzdial E L, Mann K G
Department of Medicine, Emory University, Atlanta, Georgia 30322.
Methods Enzymol. 1993;222:260-80. doi: 10.1016/0076-6879(93)22018-b.
The approaches described in this article have resulted in an increased understanding of the reaction steps involved in the stabilization and assembly of the prothrombinase complex. Because prothrombinase is considered an archetype for some of the other coagulation complexes, the quantitative information derived from these studies (Table I) provides the framework for future studies of prothrombinase and suggests experimental approaches for studies of the other analogous coagulation reactions.
本文所述方法增进了对凝血酶原酶复合物稳定和组装过程中反应步骤的理解。由于凝血酶原酶被视为其他一些凝血复合物的原型，这些研究得出的定量信息（表I）为凝血酶原酶的未来研究提供了框架，并为其他类似凝血反应的研究提出了实验方法。
