MMWR Morb Mortal Wkly Rep. 1993 Oct 29;42(42):816-20.
A unique hantavirus has been identified as the cause of the outbreak of respiratory illness (hantavirus pulmonary syndrome [HPS]) first recognized in the southwestern United States in May 1993. The habitat of the principal rodent reservoir for this virus, Peromyscus maniculatus (deer mouse), extends throughout most of the United States except the Southeast. Through October 21, 1993, HPS has been confirmed in 42 persons reported to CDC from 12 states (Figure 1). This report summarizes major clinical, pathologic, and diagnostic findings in patients with this newly recognized syndrome; addresses the use of the investigational antiviral drug ribavirin; and presents revised screening criteria for national surveillance.
一种独特的汉坦病毒已被确定为1993年5月首次在美国西南部发现的呼吸道疾病（汉坦病毒肺综合征[HPS]）疫情的病因。这种病毒的主要啮齿动物宿主白足鼠的栖息地遍布美国大部分地区，东南部除外。截至1993年10月21日，疾病控制与预防中心（CDC）已收到来自12个州报告的42例确诊汉坦病毒肺综合征病例（图1）。本报告总结了这种新发现综合征患者的主要临床、病理和诊断结果；讨论了试验性抗病毒药物利巴韦林的使用情况；并提出了国家监测的修订筛查标准。
