[Bipolar affective disorder and neuropsychiatric complications in a chronic course of thrombotic thrombocytopenic purpura. A case report].

A case report on a 43-year-old female patient with the longest chronic course of TTP known in the literature is presented. The results of comprehensive diagnostic investigations are described. In neuropsychiatric respect there exists a long standing bipolar affective disorder with a course showing a close association to this medical condition. This significant interaction is discussed in relation to the syndromal picture of the phasic bipolar psychosis and the various neuropsychiatric complications associated with recurrent cerebral thrombotic episodes.