Ansari A H, Fuller D G
South Med J. 1977 Feb;70(2):142-6. doi: 10.1097/00007611-197702000-00005.
A total of 1,607 urinary estriol determinations were performed in 447 patients with normal and complicated pregnancies. In general, the test provided reliable information concerning fetal status, particularly in pregnancies complicated by toxemia, diabetes, and postmaturity. When measured consecutively, a drop of 50% or more in estriol level usually should be considered a significant index of fetal distress. Limitations of the test and several compensatory measures aimed at minimizing inaccuracy are discussed.
对447例正常妊娠和合并症妊娠患者共进行了1607次尿雌三醇测定。一般来说,该检测能提供有关胎儿状况的可靠信息,尤其是在合并毒血症、糖尿病和过期妊娠的情况下。连续测量时,雌三醇水平下降50%或更多通常应被视为胎儿窘迫的重要指标。文中讨论了该检测的局限性以及旨在尽量减少误差的几种补偿措施。