Tóth M, Rácz K, Jakab C, Gláz E
Semmelweis Orvostudományi Egyetem, II. Belgyógyászati Klinika, Budapest.
Orv Hetil. 1993 Oct 3;134(40):2187-94.
The authors review present knowledge on multiple endocrine neoplasias types 1 and 2. They discuss in the light of recent literature data, the natural history, diagnosis, differential diagnosis and the optimal diagnostic approaches of these disorders. A short review on the therapeutic modalities draws attention to important differences between sporadic and inherited endocrine tumors. Finally, the authors emphasize recent developments about the genetic background and the importance of molecular biologic techniques, including family screening in the diagnosis of these disorders.
作者回顾了关于1型和2型多发性内分泌肿瘤的现有知识。他们根据最近的文献数据，讨论了这些疾病的自然史、诊断、鉴别诊断以及最佳诊断方法。对治疗方式的简短回顾提请注意散发性和遗传性内分泌肿瘤之间的重要差异。最后，作者强调了关于遗传背景的最新进展以及分子生物学技术的重要性，包括在这些疾病诊断中的家族筛查。
