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坏死性小肠结肠炎。关于发病机制和潜在治疗方法的新思考。

Necrotizing enterocolitis. New thoughts about pathogenesis and potential treatments.

作者信息

MacKendrick W, Caplan M

机构信息

Department of Pediatrics, Evanston Hospital, Chicago, Illinois.

出版信息

Pediatr Clin North Am. 1993 Oct;40(5):1047-59. doi: 10.1016/s0031-3955(16)38622-9.

DOI:10.1016/s0031-3955(16)38622-9
PMID:8414709
Abstract

Necrotizing enterocolitis (NEC) remains a major cause of morbidity and mortality in premature infants. An incomplete understanding of its pathogenesis has hampered efforts to devise an effective preventative strategy. New insights into the pathogenesis of NEC, particularly at the cellular and biochemical level, however, offer a rational basis for the development of new approaches to this disease.

摘要

坏死性小肠结肠炎(NEC)仍然是早产儿发病和死亡的主要原因。对其发病机制的不完全了解阻碍了制定有效预防策略的努力。然而,对NEC发病机制的新见解,特别是在细胞和生化水平上的见解,为开发针对这种疾病的新方法提供了合理依据。

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