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[人类免疫缺陷病毒感染中的关节炎。卢旺达76例病例的前瞻性研究]

[Arthritis in HIV infection. A prospective study of 76 cases in Rwanda].

作者信息

Blanche P, Saraux A, Taelman H, Sicard D, Menkes C J

机构信息

Département de Médecine interne, Hôpital Cochin, Paris.

出版信息

Presse Med. 1993;22(24):1128-32.

PMID:8415472
Abstract

A 16-month prospective study of adult patients who had been suffering from arthritis for less than one year was conducted in the Internal Medicine department of the hospital of Kigali, Rwanda. Seventy-six patients were included in the study. Out of 72 patients whose sera were tested for human immunodeficiency virus (HIV), 52 were positive, this being 72.2 percent compared with the 20.7 percent figure observed in the urban population of adults in Rwanda. Two main groups arthropathies were individualized: septic arthritis (24 patients including 19 seropositive subjects) and inflammatory rheumatism with criteria of spondyloarthropathies in some of them (34 patients, 32 tested, 28 serum positive). Thus, the finding of acute arthritis in a region with high HIV infection prevalence should suggest a possible HIV infection, especially when the arthritis itself is suggestive of this diagnosis.

摘要

在卢旺达基加利市医院内科对患有关节炎不到一年的成年患者进行了一项为期16个月的前瞻性研究。76名患者被纳入研究。在72名接受人类免疫缺陷病毒(HIV)血清检测的患者中,52名呈阳性,占72.2%,而卢旺达城市成年人口中这一比例为20.7%。确定了两种主要的关节病类型:化脓性关节炎(24例患者,其中19例血清阳性)和部分患者符合脊柱关节病标准的炎性风湿病(34例患者,32例接受检测,28例血清阳性)。因此,在HIV感染率高的地区发现急性关节炎应提示可能感染了HIV,尤其是当关节炎本身提示这一诊断时。

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