Incani R N
Departamento de Parasitología, Facultad de Ciencias de la Salud, Universidad de Carabobo, Valencia, Venezuela.
Parasitol Res. 1993;79(6):508-11. doi: 10.1007/BF00931593.
For evaluation of the degree of genetic heterogeneity in parasite and snail strains, the compatibility between Biomphalaria glabrata and Schistosoma mansoni from different geographical areas was studied. Venezuelan snails from Bárbula, Manuare (areas of schistosome transmission) and Tinaquillo (non-transmission area) and Brazilian BH snails were exposed to infection with miracidia of both the Venezuelan YT and SM strains and the Brazilian BH strain of S. mansoni. Snail-parasite compatibility was evaluated by quantifying the number of snails shedding cercariae during a period of 35 to 60 days post-infection. The best compatibility appeared to be between the Brazilian parasites and the Brazilian or Venezuelan snails. In contrast, the Brazilian snails appeared to be resistant to infection by the Venezuelan parasites tested. Paradoxically, the compatibility between the sympatric pair of Venezuelan parasites and Venezuelan snails appeared to be lower in comparison with the allopatric association of the Brazilian parasite and the Venezuelan snails. The results suggest an important degree of heterogeneity in the snail and parasite isolates studied and yield biological markers for both organisms.
为评估寄生虫和蜗牛品系的遗传异质性程度，研究了不同地理区域的光滑双脐螺与曼氏血吸虫之间的相容性。来自委内瑞拉巴尔布拉、马努阿雷（血吸虫传播地区）和蒂纳基洛（非传播地区）的蜗牛以及巴西BH蜗牛，分别用委内瑞拉YT和SM品系以及巴西BH品系的曼氏血吸虫尾蚴进行感染。通过量化感染后35至60天内排出尾蚴的蜗牛数量来评估蜗牛 - 寄生虫的相容性。最佳的相容性似乎存在于巴西寄生虫与巴西或委内瑞拉蜗牛之间。相反，巴西蜗牛似乎对所测试的委内瑞拉寄生虫感染具有抗性。矛盾的是，与巴西寄生虫和委内瑞拉蜗牛的异域组合相比，委内瑞拉同域寄生虫与委内瑞拉蜗牛之间的相容性似乎更低。结果表明，所研究的蜗牛和寄生虫分离株存在重要程度的异质性，并为这两种生物提供了生物学标记。
