Aboulghar M A, Mansour R T, Serour G I, Sattar M A, Amin Y M, Elattar I
Egyptian IVF-ET Center, Cairo University.
Obstet Gynecol. 1993 Jan;81(1):108-11.
To assess the value of intensive intravenous (IV) fluid therapy and ascitic fluid aspiration in the management of severe ovarian hyperstimulation syndrome.
Forty-two women with severe ovarian hyperstimulation syndrome were treated by ultrasonically guided transvaginal aspiration of ascitic fluid and IV fluid infusion. Ten women with the same condition treated conservatively constituted a comparison group. The main outcome measures included percentage change in hematocrit, creatinine clearance, and urine output before and after aspiration. The duration of hospital stay was compared between the groups.
Marked improvement of symptoms and general condition followed soon after aspiration. Hematocrit readings decreased by 22%, creatinine clearance increased by 79.3%, and urine output increased by 220.7%. The average volume of aspirated fluid was 3900 mL. The average duration of hospital stay was 3.8 days in the treated women. In the comparison group, severe symptoms and electrolyte imbalance continued for an average of 9 days, and the average hospital stay was 11 days.
Intensive IV fluid therapy and transvaginal aspiration of ascitic fluid are safe and effective in improving symptoms, preventing complications, and shortening the hospital stay in severe ovarian hyperstimulation syndrome.
评估强化静脉输液治疗及腹水抽吸在重度卵巢过度刺激综合征管理中的价值。
对42例重度卵巢过度刺激综合征患者采用经阴道超声引导下腹水抽吸及静脉输液治疗。10例病情相同的患者采用保守治疗作为对照组。主要观察指标包括抽吸前后血细胞比容、肌酐清除率及尿量的变化百分比。比较两组患者的住院时间。
抽吸后症状及一般状况很快有明显改善。血细胞比容读数下降22%，肌酐清除率提高79.3%，尿量增加220.7%。平均抽吸腹水量为3900 mL。治疗组患者的平均住院时间为3.8天。对照组中，严重症状及电解质失衡平均持续9天，平均住院时间为11天。
强化静脉输液治疗及经阴道腹水抽吸在改善重度卵巢过度刺激综合征症状、预防并发症及缩短住院时间方面安全有效。
