Picton T D, Owen D A, MacDonald W C
British Columbia Cancer Agency, Canada.
Cancer. 1993 Jan 1;71(1):5-8. doi: 10.1002/1097-0142(19930101)71:1<5::aid-cncr2820710103>3.0.co;2-c.
Adenocarcinoma of the gastric cardia and/or lower esophagus differs from cancer of the more distal stomach.
The authors compared the proportion of patients with these two types of cancer who underwent surgery for peptic ulcers more than 5 years before the diagnosis of cancer during the periods 1977-82 and 1983-88.
The total number of patients with esophagocardiac cancer increased from 99-241 between the two periods, but the number with previous ulcer surgery remained the same (n = 7) in each period. The total number of more distal gastric cancers decreased from 262 to 237 between the two periods, but the number with previous ulcer surgery increased from 9-26 (P = 0.002). Only 4 of 14 patients with esophagocardiac cancer and a previous ulcer had a partial gastrectomy compared with 27 of 35 patients with more distal gastric cancers (P = 0.005).
These data indicate a relationship between partial gastrectomy and the late development of gastric cancer, but this finding is confined to cancers not involving the cardia.
贲门和/或食管下段腺癌与胃远端癌不同。
作者比较了1977 - 1982年和1983 - 1988年期间，这两种类型癌症患者中在癌症诊断前5年以上因消化性溃疡接受手术的比例。
两个时期之间，食管贲门癌患者总数从99例增加到241例，但每个时期之前接受过溃疡手术的患者数量保持不变（n = 7）。两个时期之间，胃远端癌总数从262例减少到237例，但之前接受过溃疡手术的患者数量从9例增加到26例（P = 0.002）。14例有过溃疡手术史的食管贲门癌患者中只有4例行胃部分切除术，而35例胃远端癌患者中有27例行胃部分切除术（P = 0.005）。
这些数据表明胃部分切除术与胃癌的晚期发生之间存在关联，但这一发现仅限于不涉及贲门的癌症。
