在一名具有抗Yta抗体的受者体内，Yt(a+)红细胞被快速破坏。

Rapid in vivo destruction of Yt(a+) erythrocytes in a recipient with anti-Yta.

作者信息

Ballas S K, Sherwood W C

出版信息

Transfusion. 1977 Jan-Feb;17(1):65-6. doi: 10.1046/j.1537-2995.1977.17177128889.x.

DOI:10.1046/j.1537-2995.1977.17177128889.x

Abstract

A patient with anti-Cartwright (anti-Yta) is reported. Immunohematologic studies showed this antibody to be an IgG immunoglobulin that does not bind complement. A 51Cr red blood cell survival study resulted in a greatly reduced half-life of less than six hours of Yt(a+) cells. The antibody titer increased threefold after the red blood cell survival study. Determination of red cell survival is indicated when crossmatch-incompatible blood transfusion is considered.

摘要

报告了一例抗卡特赖特（抗Yta）患者。免疫血液学研究表明，该抗体为不结合补体的IgG免疫球蛋白。51铬红细胞存活研究显示，Yt(a+)细胞的半衰期大幅缩短至不到6小时。红细胞存活研究后抗体效价增加了三倍。当考虑交叉配血不相容的输血时，建议进行红细胞存活测定。