Hallander H O, Reizenstein E, Renemar B, Rasmuson G, Mardin L, Olin P
Department of Bacteriology, National Bacteriological Laboratory, Stockholm, Sweden.
J Clin Microbiol. 1993 Jan;31(1):50-2. doi: 10.1128/jcm.31.1.50-52.1993.
Nasopharyngeal samples were collected from 117 children by aspiration from one nostril and by swab from the other one and cultured for Bordetella pertussis. Among 33 culture-positive specimens, there were 30 positive aspirates and 26 positive swab specimens. Aspirates are easily divided and saved for investigations with other assays which may further improve diagnostic sensitivity. As the aspiration technique was also preferred by nurses and parents, it was recommended and chosen for a planned pertussis vaccine efficacy trial to take place in Sweden from 1992 to 1995.
通过从一个鼻孔抽吸和从另一个鼻孔擦拭的方式，从117名儿童中采集鼻咽样本，并对其进行百日咳博德特氏菌培养。在33份培养阳性标本中，有30份抽吸样本呈阳性，26份擦拭样本呈阳性。抽吸样本易于分离并保存，可用于其他检测方法的研究，这可能会进一步提高诊断敏感性。由于护士和家长也更喜欢抽吸技术，因此在1992年至1995年于瑞典进行的一项计划中的百日咳疫苗效力试验中，推荐并选用了该技术。
