Brooner R K, Greenfield L, Schmidt C W, Bigelow G E
Johns Hopkins University School of Medicine, Baltimore.
Am J Psychiatry. 1993 Jan;150(1):53-8. doi: 10.1176/ajp.150.1.53.
Antisocial personality disorder in drug abusers has been associated with poor treatment outcome. The authors examined the relationship between diagnosis of antisocial personality and HIV infection.
Subjects were 272 intravenous drug abusers, 140 (52%) of whom were in methadone treatment. Subjects were given an HIV risk behavior interview before diagnostic interviewing and HIV testing.
Using the DSM-III-R definition, the authors found that 119 (44%) of the subjects met criteria for antisocial personality. Significantly more of the subjects with antisocial personality (18% [N = 21] than of the subjects without antisocial personality (8% [N = 12]) had HIV infection. The diagnosis of antisocial personality disorder was associated with a significantly higher odds ratio of infection independent of ethnicity, gender, and treatment status.
Antisocial personality is a risk factor for HIV infection among intravenous drug abusers.
吸毒者中的反社会人格障碍与治疗效果不佳有关。作者研究了反社会人格诊断与艾滋病毒感染之间的关系。
研究对象为272名静脉吸毒者，其中140人（52%）正在接受美沙酮治疗。在进行诊断性访谈和艾滋病毒检测之前，对研究对象进行了艾滋病毒风险行为访谈。
根据《精神疾病诊断与统计手册》第三版修订版（DSM-III-R）的定义，作者发现119名（44%）研究对象符合反社会人格的标准。反社会人格的研究对象中感染艾滋病毒的比例（18% [N = 21]）显著高于无反社会人格的研究对象（8% [N = 12]）。反社会人格障碍的诊断与感染几率显著较高相关，且不受种族、性别和治疗状态的影响。
反社会人格是静脉吸毒者感染艾滋病毒的一个风险因素。
