Conrad S A, Eggerstedt J M, Morris V F, Romero M D
Department of Medicine (Critical Care), Louisiana State University Medical Center, Shreveport 71130-3932.
Chest. 1993 Jan;103(1):158-61. doi: 10.1378/chest.103.1.158.
Patients with severe respiratory failure undergoing conventional mechanical ventilation typically are exposed to levels of ventilator support that place the patient at risk of barotrauma or oxygen toxicity. In severe cases, gas exchange may be inadequate despite maximal ventilator support. We report two cases of advanced respiratory failure in which augmentation of gas exchange was provided for prolonged periods (18 and 13 days) with an intravenacaval hollow-fiber membrane oxygenator (IVOX). Following implantation, significant reductions in ventilator support were possible with improvement in arterial blood gas values. No significant complications were noted. IVOX can provide clinically useful augmentation of gas exchange in respiratory failure and can be used for prolonged periods.
接受传统机械通气的严重呼吸衰竭患者通常会受到一定水平的通气支持，这使患者有发生气压伤或氧中毒的风险。在严重病例中，尽管给予最大程度的通气支持，气体交换仍可能不足。我们报告了两例晚期呼吸衰竭病例，其中使用腔静脉中空纤维膜氧合器（IVOX）长时间（18天和13天）增强气体交换。植入后，在动脉血气值改善的情况下，可以显著减少通气支持。未观察到明显并发症。IVOX可以在呼吸衰竭中提供临床上有用的气体交换增强，并且可以长时间使用。
