Chiu A, Pegram P S, Haponik E F
Department of Medicine, Stanford University, California.
J Thorac Imaging. 1993 Winter;8(1):69-78.
Hypersensitivity pneumonitis is an important but underdiagnosed form of interstitial lung disease. Its clinical hallmark is recurrent or chronic pulmonary symptoms of variable severity associated with an array of systemic symptoms but without extrapulmonary structural abnormalities. Clinical suspicion is the key to diagnosis, which is supported by establishing an environmental or occupational exposure to a causative inhaled antigen; by excluding infectious and other causes of recurrent, migratory, or progressive radiologic lung abnormalities; and by demonstrating antigen-specific antibodies in the serum. Two cases of hypersensitivity pneumonitis are described that illustrate the widely variable clinical, laboratory, and radiologic presentations and emphasize the importance of diagnosing this treatable condition.
过敏性肺炎是一种重要但诊断不足的间质性肺疾病形式。其临床特征是反复出现或慢性的肺部症状，严重程度不一，伴有一系列全身症状，但无肺外结构异常。临床怀疑是诊断的关键，通过确定环境或职业性接触致病吸入抗原、排除反复出现、游走性或进行性肺部影像学异常的感染及其他原因，以及在血清中检测到抗原特异性抗体来支持诊断。本文描述了两例过敏性肺炎病例，说明了其在临床、实验室和影像学表现上的广泛差异，并强调了诊断这种可治疗疾病的重要性。
