Kuzniecky R, Burgard S, Faught E, Morawetz R, Bartolucci A
University of Alabama, Birmingham Epilepsy Center, Departments of Neurology 35294.
Arch Neurol. 1993 Jan;50(1):65-9. doi: 10.1001/archneur.1993.00540010059018.
The predictive value of magnetic resonance imaging (MRI) was assessed by a prospective study of 34 patients selected for surgical treatment of temporal lobe epilepsy. The MRIs were interpreted using standardized visual diagnostic criteria and the imaging findings were correlated with the surgical outcome. Lateralized MRI abnormalities were found in 25 (74%) of 34 patients. Significant associations were found between either the presence of a restricted foreign-tissue lesion or hippocampal atrophy and an excellent surgical outcome. An abnormal MRI had an 82% predictive value and a normal MRI had a 56% predictive value for surgical success. A history of febrile convulsions and the presence of hippocampal atrophy best predicted outcome (predictive value, 86%). These results suggest that specific MRI findings in candidates for temporal lobe epilepsy surgery are predictive of surgical outcome. The information provided by MRI may be of value for counseling patients prior to surgical intervention.
通过对34例因颞叶癫痫接受手术治疗的患者进行前瞻性研究，评估了磁共振成像（MRI）的预测价值。使用标准化的视觉诊断标准解读MRI，并将影像学结果与手术结果进行关联。34例患者中有25例（74%）发现了侧化MRI异常。发现局限性外源性组织病变或海马萎缩的存在与良好的手术结果之间存在显著关联。异常MRI对手术成功的预测价值为82%，正常MRI的预测价值为56%。热性惊厥病史和海马萎缩的存在对手术结果的预测性最佳（预测价值为86%）。这些结果表明，颞叶癫痫手术候选者的特定MRI表现可预测手术结果。MRI提供的信息可能对手术干预前咨询患者有价值。
