Vinograd I, Granot E, Ron N, Klin B, Tauber T, Segal M
Department of Pediatric Surgery, Assaf Harofeh Medical Center, Zerifin, Israel.
J Clin Gastroenterol. 1993 Jan;16(1):40-4. doi: 10.1097/00004836-199301000-00011.
Chronic diffuse varioliform gastritis is an uncommon, subacute, inflammatory gastric mucosal disease characterized by swollen congested rugae and disseminated mucosal erosions. The entity is exceptionally rare in children. The spectrum of reported symptoms is broad; frank hematemesis has never been reported in childhood. We present a child in whom the disease had a remarkably unusual clinical course. Because many caretakers were unaware of the existence of the disease in children, the patient had numerous hospitalizations and surgical procedures, until massive gastric bleeding resulted in unavoidable emergency total gastrectomy. Microscopical examination and immunofluorescent staining of the gastric mucosa confirmed the diagnosis of chronic diffuse varioliform gastritis.