Farrell M A, Quiggins P A, Eller J D, Owle P A, Miner K M, Walkingstick E S
Cherokee Indian Hospital, North Carolina.
Diabetes Care. 1993 Jan;16(1):253-6. doi: 10.2337/diacare.16.1.253.
To determine the prevalence of diabetes and selected complications among the Eastern Band of Cherokee Indians in North Carolina.
Multiple IHS data systems were used to determine diabetes prevalence and complication rates. The RPMS was used to identify diabetes cases as of April 1989, degree of Indian inheritance, cardiovascular diseases (including hypertension), and retinopathy. Data on laser treatments and LEA were obtained from individual registries. Information on ESRD was obtained by a research assistant. The IHS Ambulatory Patient Care reporting system was used to calculate the number of diabetic patients for the years 1982-1987. The IHS user population was used as the denominator. Rates were age-adjusted to the 1980 U.S. population and diabetic population by the direct method.
Using clinical records, the age-adjusted prevalence of diabetes in 1988 was 105.6/1000 people, four times the U.S. rate. Rates of diabetes were highest in the groups with the highest degree of Indian inheritance. LEAs occurred among diabetic patients at three times the rate for the U.S. Between 1985 and 1989, new cases of ESRD occurred at a crude annualized rate of 578/million, approximately six times the rate for U.S. whites.
Diabetes presents a major burden to the Eastern Band of Cherokees. The limitation inherent in this study probably result in underestimation of the prevalence of diabetes and its complications in the community. Future studies are needed to assess the impact of medical and preventive programs on diabetes prevalence and complications in this community.
确定北卡罗来纳州切诺基印第安人东部部落中糖尿病及部分并发症的患病率。
使用多个印第安卫生服务局(IHS)数据系统来确定糖尿病患病率和并发症发生率。利用资源与病人管理系统(RPMS)来识别截至1989年4月的糖尿病病例、印第安人遗传程度、心血管疾病(包括高血压)和视网膜病变。激光治疗和下肢截肢(LEA)的数据来自各个登记处。通过一名研究助理获取终末期肾病(ESRD)的信息。使用IHS门诊病人护理报告系统来计算1982 - 1987年糖尿病患者的数量。IHS的用户群体作为分母。采用直接法将患病率按年龄调整至1980年美国人口和糖尿病患者人口的水平。
根据临床记录,1988年经年龄调整后的糖尿病患病率为105.6/1000人,是美国患病率的四倍。印第安人遗传程度最高的群体中糖尿病患病率最高。糖尿病患者下肢截肢的发生率是美国的三倍。1985年至1989年期间,终末期肾病新发病例的年化粗发病率为578/百万,约为美国白人发病率的六倍。
糖尿病给切诺基东部部落带来了沉重负担。本研究固有的局限性可能导致对该社区糖尿病及其并发症患病率的低估。未来需要开展研究,以评估医疗和预防项目对该社区糖尿病患病率及并发症的影响。