服用氟西汀后帕金森病残疾程度加重。
Increase of Parkinson disability after fluoxetine medication.
作者信息
Steur E N
机构信息
Movement Disorder Unit, Hospital Medisch Spectrum Twente, Enschede, Holland.
出版信息
Neurology. 1993 Jan;43(1):211-3. doi: 10.1212/wnl.43.1_part_1.211.
PMID:8423889
Abstract
Depression is a major clinical feature of Parkinson's disease. We report the increased amount of motor disability in four patients with idiopathic Parkinson's disease after exposure to the antidepressant fluoxetine. The possibility of a clinically relevant dopamine-antagonistic capacity of fluoxetine in Parkinson's disease patients must be considered.
摘要
抑郁症是帕金森病的主要临床特征。我们报告了4例特发性帕金森病患者在服用抗抑郁药氟西汀后运动功能障碍加重的情况。必须考虑氟西汀在帕金森病患者中具有临床相关多巴胺拮抗能力的可能性。
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