Matsui K, Kitagawa M
Department of Pathology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.
Am J Gastroenterol. 1993 Feb;88(2):253-7.
To clarify the clinical and histological features of polyps in the duodenal bulb (DB), we studied, clinicopathologically, a total of 263 patients (179 male, 84 female) with polyps in the DB. The patients were 13-86 yr of age (average age, 57.1 yr). On endoscopy, a semipedunculated or pedunculated polyp with a relatively large size was seen in 33 patients, and small polyps, either single or multiple, were incidentally discovered in 230 patients. Histological examination of the biopsied specimens from polyps revealed gastric tissue in 182 cases (69.2%), cyst formation in 51 (19.4%), and other miscellaneous lesions (tubular adenoma, Brunner's gland hyperplasia, etc.) in 30 (11.4%). With regard to the gastric tissue, a "full-thickness" or "incomplete" body-type mucosa was identified in 27 cases of polyps, and hyperplastic surface epithelium was recognized in 155. Forty cases of hyperplastic surface epithelium-type polyps were subclassified as "pyloric"-type mucosa, because pyloric gland-like components seen under the surface epithelium were identical to those of the gastric antrum. It was reconfirmed that small polyps with little or no clinical significance could be produced by various histological features.
为阐明十二指肠球部（DB）息肉的临床和组织学特征，我们对263例DB部息肉患者（男性179例，女性84例）进行了临床病理研究。患者年龄为13 - 86岁（平均年龄57.1岁）。在内镜检查中，33例患者可见相对较大的半蒂状或有蒂息肉，230例患者偶然发现单个或多个小息肉。对息肉活检标本进行组织学检查，结果显示182例（69.2%）为胃组织，51例（19.4%）为囊肿形成，30例（11.4%）为其他杂类病变（管状腺瘤、Brunner腺增生等）。关于胃组织，27例息肉中鉴定出“全层”或“不完全”的胃体部黏膜，155例可见增生的表面上皮。40例增生表面上皮型息肉被归类为“幽门”型黏膜，因为表面上皮下所见的幽门腺样成分与胃窦的相同。再次证实，各种组织学特征均可产生临床意义不大或无临床意义的小息肉。
