Gil J C, Cedillo R L, Mayagoitia B G, Paz M D
Microbiological Research Center, Puebla University, Mexico.
Ann Allergy. 1993 Jan;70(1):23-5.
Asthmatic patients frequently develop wheezing after respiratory tract infection. Mycoplasma pneumoniae causes respiratory tract infections in children and in adults. The purpose of this study was to determine the frequency of recovery of M. pneumoniae from patients with asthma. Seventy-seven patients with asthma and 88 persons without asthma or any other respiratory tract disease (controls) were included in the study. Ages ranged from 8 months to 31 years. Throat swabs were taken and deposited in egg yolk broth with methylene blue in order to isolate M. pneumoniae. The bacterium was identified using inhibition of growth with homologous antiserum. The isolation rate in patients with asthma was 24.7% while that in controls was 5.7% (P < .01). The results suggest that M. pneumoniae colonizes a higher percentage of patients with asthma than controls and could possibly have induced the wheezing.
哮喘患者在呼吸道感染后常出现喘息。肺炎支原体可引起儿童和成人的呼吸道感染。本研究的目的是确定哮喘患者中肺炎支原体的检出率。本研究纳入了77例哮喘患者和88例无哮喘或其他呼吸道疾病的人（对照组）。年龄范围为8个月至31岁。采集咽拭子并接种于含亚甲蓝的蛋黄肉汤中以分离肺炎支原体。使用同源抗血清抑制生长来鉴定该细菌。哮喘患者的分离率为24.7%，而对照组为5.7%（P <.01）。结果表明，与对照组相比，肺炎支原体在哮喘患者中的定植率更高，可能诱发了喘息。
