Runowicz C D, Smith H O, Goldberg G L
Department of Obstetrics and Gynecology, Albert Einstein College of Medicine, Montefiore Medical Center, New York, NY 10461.
Curr Opin Obstet Gynecol. 1993 Feb;5(1):92-8.
In the past decade, neoadjuvant and concomitant multimodality therapies have been studied in patients with cervical cancer. The past year has witnessed more pilot studies confirming the feasibility of multimodality therapy. It is now time to move to prospective randomized clinical trials to determine the effects on disease-free intervals, to examine survival rates, and to define the ideal chemotherapeutic regimen and relationship to radiation therapy or surgery.
在过去十年中,人们对宫颈癌患者进行了新辅助和同步多模式治疗的研究。过去一年见证了更多的试点研究证实了多模式治疗的可行性。现在是时候开展前瞻性随机临床试验,以确定其对无病间期的影响、研究生存率,并确定理想的化疗方案以及与放疗或手术的关系。