Kraay M J, Goldberg V M, Herbener T E
University Hospital of Cleveland, Ohio.
Clin Orthop Relat Res. 1993 Jan(286):18-26.
Screening vascular ultrasonography was performed postoperatively on 164 consecutive patients being treated with total knee arthroplasty (203 total knee prostheses). This consisted of examination of the femoral and popliteal veins of the operative extremity with color flow and duplex ultrasonography one week postoperatively. All patients received deep venous thrombosis (DVT) prophylaxis with sequential compressive pneumatic stockings, low-dose warfarin, continuous passive motion, and early mobilization. All patients were observed prospectively for thromboembolic sequelae for a minimum of six months postoperatively. The screening study was significantly limited in six (3%) of the 203 total knee prostheses. The overall incidence of sonographically detected proximal DVT or symptomatic calf vein thrombosis was 3% (6/203), and the incidence of symptomatic pulmonary embolism was 2% (4/203). Four of the ten thromboembolic complications occurred after hospital discharge. Results of this study suggest that duplex ultrasonography can be a useful screening method for identification of venous thrombosis after TKA. Patients with asymptomatic proximal DVT can be identified and appropriately treated before development of serious thromboembolic complications. Routine screening for DVT after TKA can avoid the considerable expense, inconvenience, and potential risk of complications associated with prolonged postoperative prophylactic anticoagulation. The combination of sequential compressive stockings, early mobilization, and low-dose warfarin appears to be a safe and effective prophylactic regimen against venous thromboembolic disease in these high-risk patients.
对连续接受全膝关节置换术治疗的164例患者(共203个全膝关节假体)术后进行了血管超声筛查。这包括在术后1周用彩色血流和双功超声检查手术肢体的股静脉和腘静脉。所有患者均接受了序贯加压气圈、小剂量华法林、持续被动运动和早期活动等深静脉血栓形成(DVT)预防措施。所有患者均在术后前瞻性观察至少6个月的血栓栓塞后遗症情况。在203个全膝关节假体中,有6个(3%)的筛查研究受到显著限制。超声检查发现的近端DVT或有症状的小腿静脉血栓形成的总发生率为3%(6/203),有症状的肺栓塞发生率为2%(4/203)。10例血栓栓塞并发症中有4例发生在出院后。本研究结果表明,双功超声检查可作为全膝关节置换术后识别静脉血栓形成的一种有用的筛查方法。无症状近端DVT患者可在严重血栓栓塞并发症发生前得到识别并进行适当治疗。全膝关节置换术后常规筛查DVT可避免与延长术后预防性抗凝相关的可观费用、不便和潜在并发症风险。序贯加压弹力袜、早期活动和小剂量华法林联合应用似乎是这些高危患者预防静脉血栓栓塞性疾病的一种安全有效的预防方案。