Halpin S, Kingsley D
Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, England.
AJNR Am J Neuroradiol. 1993 Jan-Feb;14(1):119-22.
Calcification occurs in many benign and malignant neurologic disorders. We describe two patients with cerebral glioma, in whom the disappearance of cerebral calcification was evidence of local malignant change. We discuss the underlying chemical mechanisms that result in tissue calcification, and postulate that calcification may disappear in the presence of a malignant tumor because of a decrease in the pH of the microenvironment.
钙化发生于许多良性和恶性神经系统疾病中。我们描述了两名患有脑胶质瘤的患者，其脑内钙化的消失是局部恶性变化的证据。我们讨论了导致组织钙化的潜在化学机制，并推测在恶性肿瘤存在的情况下，钙化可能会因微环境pH值降低而消失。
