Chiriboga D E, Yarzebski J, Goldberg R J, Chen Z, Gurwitz J, Gore J M, Alpert J S, Dalen J E
Department of Medicine, University of Massachusetts Medical School, Worcester 01655.
Am J Cardiol. 1993 Feb 1;71(4):268-73. doi: 10.1016/0002-9149(93)90789-f.
This study compares the overall use, as well as temporal trends, of various diagnostic and revascularization procedures for acute myocardial infarction (AMI) in men and women. The study sample comprised a total of 2,924 men and 1,838 women with validated AMI admitted to any of the 16 teaching and community hospitals in the Worcester, Massachusetts, metropolitan area during 1975, 1978, 1981, 1984, 1986 and 1988. During the period under study there was a significant increase in use of each of the examined procedures during hospitalization for AMI in both men and women. Increasing use of multiple procedures was also seen for each of the sexes. After controlling for a variety of demographic and clinical factors that might affect utilization rates, men were marginally more likely to undergo radionuclide ventriculography, and significantly more likely to undergo Holter monitoring, exercise treadmill testing, cardiac catheterization, and percutaneous transluminal coronary angioplasty than women. However, there were no gender differences in the use of coronary artery bypass grafting. On the other hand, men were significantly less likely to undergo echocardiography. The results of this multihospital, population-based study suggest sex differences in the use of several diagnostic and revascularization procedures during hospitalization for AMI. These differences may be attributed to physicians' practice patterns, although gender bias in the delivery of medical care cannot be excluded. Temporal trends in increased overall use of these procedures raise questions about cost-effectiveness that need to be further addressed.
本研究比较了男性和女性急性心肌梗死(AMI)患者各种诊断和血运重建程序的总体使用情况以及时间趋势。研究样本包括1975年、1978年、1981年、1984年、1986年和1988年期间在马萨诸塞州伍斯特市大都市区的16家教学医院和社区医院中收治的2924名男性和1838名经证实患有AMI的女性。在研究期间,男性和女性AMI住院期间所检查的每种程序的使用均显著增加。两性中使用多种程序的情况也在增加。在控制了可能影响使用率的各种人口统计学和临床因素后,男性比女性略微更有可能接受放射性核素心室造影,并且显著更有可能接受动态心电图监测、运动平板试验、心导管检查和经皮腔内冠状动脉成形术。然而,在冠状动脉旁路移植术的使用方面没有性别差异。另一方面,男性接受超声心动图检查的可能性显著较低。这项基于多医院人群的研究结果表明,AMI住院期间在几种诊断和血运重建程序的使用上存在性别差异。这些差异可能归因于医生的执业模式,尽管不能排除医疗服务中的性别偏见。这些程序总体使用增加的时间趋势引发了关于成本效益的问题,需要进一步探讨。