Grantham-McGregor S M
Tropical Metabolism Research Unit, University of the West Indies, Mona Kingston, Jamaica.
Am J Clin Nutr. 1993 Feb;57(2 Suppl):303S-309S. doi: 10.1093/ajcn/57.2.303S.
Methodological issues and problems in studies of the effects of protein-energy malnutrition (PEM) and child development are discussed with reference to our experience in Jamaica. The usefulness of defining PEM by stunting, wasting, and edema is stressed. Difficulties in achieving reliable and valid measurements of mental development and behavior in Third World children, and allowing for the confounding and possibly interacting effects of social background, are discussed. Problems associated with different approaches are outlined.
结合我们在牙买加的经验，讨论了蛋白质 - 能量营养不良（PEM）与儿童发育影响研究中的方法学问题。强调了通过发育迟缓、消瘦和水肿来定义PEM的有用性。讨论了在第三世界儿童中获得可靠且有效的心理发育和行为测量结果的困难，以及考虑社会背景的混杂和可能的相互作用影响的问题。概述了与不同方法相关的问题。
