Pleasant R S, Baker G J, Foreman J H, Eurell J A, Losonsky J M
Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana.
Am J Vet Res. 1993 Jan;54(1):7-12.
Navicular bone intraosseous pressure, gross pathologic, histologic, and histochemical data were collected from 8 horses with navicular disease and 4 control horses. Simultaneous navicular bone intraosseous, medial palmar arterial, and saphenous venous pressures were measured for the left and right forelimbs of each horse under general anesthesia. Gross pathologic evaluation included grading of changes on the flexor surface of the navicular bone. Safranin-O-fast green-stained sections were used for histologic-histochemical grading of the hyaline articular and fibrocartilage surfaces of the navicular bones. Hematoxylin and eosin-stained sections were used for morphologic evaluation of the marrow spaces of navicular bones. Mean navicular bone intraosseous pressure for horses with navicular disease was significantly (P < 0.001) higher than that for controls. Differences in medical palmar arterial or saphenous venous pressures were not significant between groups. The median flexor surface gross pathologic and histologic-histochemical fibrocartilage scores for horses with navicular disease were significantly (P < 0.001) more severe than those for control horses. The histologic-histochemical hyaline cartilage scores for control horses and those for horses with navicular disease were not significantly different. Fibrosis of the marrow spaces beneath the flexor cortex of horses with navicular disease was more pronounced than that of control horses.
从8匹患有舟状骨病的马和4匹对照马身上收集舟状骨骨内压、大体病理学、组织学和组织化学数据。在全身麻醉下，测量每匹马左前肢和右前肢的舟状骨骨内压、掌内侧动脉压和隐静脉压。大体病理学评估包括对舟状骨屈面变化的分级。番红O-固绿染色切片用于对舟状骨透明关节面和纤维软骨面进行组织学-组织化学分级。苏木精和伊红染色切片用于对舟状骨骨髓腔进行形态学评估。患有舟状骨病的马的平均舟状骨骨内压显著高于对照组（P < 0.001）。两组之间掌内侧动脉压或隐静脉压的差异不显著。患有舟状骨病的马的屈面大体病理学和组织学-组织化学纤维软骨评分中位数显著高于对照马（P < 0.001）。对照马和患有舟状骨病的马的组织学-组织化学透明软骨评分没有显著差异。患有舟状骨病的马屈面皮质下方骨髓腔的纤维化比对照马更明显。
