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主动脉手术中的自体输血:Haemocell System 350血液回收机

Autotransfusion in aortic surgery: the Haemocell System 350 cell saver.

作者信息

Kalra M, Beech M J, al-Khaffaf H, Charlesworth D

机构信息

Department of Surgery, University Hospital of South Manchester, UK.

出版信息

Br J Surg. 1993 Jan;80(1):32-5. doi: 10.1002/bjs.1800800111.

Abstract

Autotransfusion was performed during elective abdominal aortic reconstruction in ten patients using the recently developed Haemocell System 350. A mean of 60 per cent of total blood loss was salvaged, and during operation each patient was autotransfused 1 unit. Good preservation of cellular components, including platelets, was seen after processing with the device, which uses a vortex mixing filter for cell separation. There was no evidence of coagulopathy; mean free plasma haemoglobin levels were slightly raised (17 mg/dl) and plasma heparin concentration was negligible (0.10 units/ml) 4 h after surgery. A transient drop in plasma fibrinogen levels and the appearance of fibrin degradation products in low concentrations (mean 1.5 mg/l) were seen. Oxyhaemoglobin dissociation curves showed the salvaged red blood cells to have a normal affinity for oxygen. Renal and hepatic function remained unaltered and there were no complications attributable to autotransfusion. The device was easy to handle and a trained operator was not required.

摘要

在10例择期腹主动脉重建手术中,使用最近研发的血液细胞系统350进行了自体输血。平均挽回了总失血量的60%,手术过程中每位患者自体输血1个单位。在用该设备处理后,观察到包括血小板在内的细胞成分得到了良好保存,该设备使用涡旋混合过滤器进行细胞分离。没有凝血功能障碍的证据;术后4小时,平均游离血浆血红蛋白水平略有升高(17mg/dl),血浆肝素浓度可忽略不计(0.10单位/ml)。观察到血浆纤维蛋白原水平短暂下降,并出现低浓度的纤维蛋白降解产物(平均1.5mg/l)。氧合血红蛋白解离曲线显示,回收的红细胞对氧气具有正常亲和力。肾功能和肝功能保持不变,没有因自体输血导致的并发症。该设备易于操作,不需要训练有素的操作人员。

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