在小鼠模型中，对半抗原的耐受性可预防特异性迟发型超敏反应和肺间质纤维化。 - Suppr | 超能文献

Tolerance to hapten prevents specific delayed type hypersensitivity and pulmonary interstitial fibrosis in the mouse model.

作者信息

Kimura R, Hu H, Stein-Streilein J

机构信息

Department of Medicine, University of Miami School of Medicine 33101.

出版信息

Chest. 1993 Feb;103(2 Suppl):122S-124S. doi: 10.1378/chest.103.2_supplement.122s.

DOI:10.1378/chest.103.2_supplement.122s

Abstract

摘要

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Tolerance to hapten prevents specific delayed type hypersensitivity and pulmonary interstitial fibrosis in the mouse model.在小鼠模型中，对半抗原的耐受性可预防特异性迟发型超敏反应和肺间质纤维化。

Chest. 1993 Feb;103(2 Suppl):122S-124S. doi: 10.1378/chest.103.2_supplement.122s.

2

Immunological tolerance to hapten prevents subsequent induction of hapten-immune pulmonary interstitial fibrosis (HIPIF).对半抗原的免疫耐受可防止随后诱导的半抗原免疫性肺间质纤维化（HIPIF）。

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Delayed-type hypersensitivity responses regulate collagen deposition in the lung.迟发型超敏反应调节肺内胶原蛋白的沉积。

Immunology. 1992 Dec;77(4):550-5.

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Interruption of tolerance toward a haptenic initiator of delayed-type hypersensitivity.对迟发型超敏反应的半抗原引发剂的耐受性中断。

J Immunol. 1983 Jun;130(6):2561-4.

5

Pulmonary interstitial fibrosis induced in hapten-immune hamsters.半抗原免疫仓鼠诱导的肺间质纤维化

Am Rev Respir Dis. 1987 Jul;136(1):119-23. doi: 10.1164/ajrccm/136.1.119.

6

Persistent pulmonary interstitial fibrosis, induced by immune response to TNP, is associated with altered mRNA procollagen type I:III ratio.由对三硝基苯（TNP）的免疫反应诱导的持续性肺间质纤维化与I型前胶原和III型前胶原mRNA比例的改变有关。

Reg Immunol. 1992 Nov-Dec;4(6):391-400.

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A role for T cells in the induction of airway hyperreactivity.T细胞在气道高反应性诱导中的作用。

Agents Actions Suppl. 1990;31:169-74. doi: 10.1007/978-3-0348-7379-6_22.

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Tolerogenic APC generate CD8+ T regulatory cells that modulate pulmonary interstitial fibrosis.耐受性抗原呈递细胞产生可调节肺间质纤维化的CD8+调节性T细胞。

J Immunol. 2004 Jan 1;172(1):178-85. doi: 10.4049/jimmunol.172.1.178.

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Soluble proteins and haptens on bone marrow-derived dendritic cells are presented to host CD4 T cells in an MHC-restricted manner.骨髓来源的树突状细胞上的可溶性蛋白质和半抗原以MHC限制的方式呈递给宿主CD4 T细胞。

Int Immunol. 2002 May;14(5):493-502. doi: 10.1093/intimm/14.5.493.

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Hapten-specific T cell lines mediating delayed hypersensitivity to contact-sensitizing agents.对半抗原致敏剂介导迟发型超敏反应的半抗原特异性T细胞系。

J Exp Med. 1982 Jul 1;156(1):300-5. doi: 10.1084/jem.156.1.300.

引用本文的文献

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Induction of lung fibrosis in the mouse by intratracheal instillation of fluorescein isothiocyanate is not T-cell-dependent.通过气管内滴注异硫氰酸荧光素在小鼠中诱导肺纤维化不依赖于T细胞。

Am J Pathol. 1999 Nov;155(5):1773-9. doi: 10.1016/S0002-9440(10)65493-4.

2

The regulation of pulmonary immunity.肺部免疫的调节

Adv Immunol. 1995;59:369-455. doi: 10.1016/s0065-2776(08)60634-3.