Injectable collagen and autoimmune disease.

BACKGROUND

The media and litigation in the United States have alleged a link between the use of injectable bovine collagen and the development of autoimmune disease, specifically dermatomyositis/polymyositis.

OBJECTIVE

To present the scientific and epidemiologic data with regard to this issue.

METHODS

Literature was reviewed as well as reports to Collagen Corporation and the litigation.

RESULTS

After review of the literature and review of data currently available to Collagen Corporation, no link can be established at this time between collagen injectable material and autoimmune disease, specifically dermatomyositis/polymyositis.

CONCLUSION

There are no epidemiologic or scientific data to support the alleged link in the media and litigation between injectable bovine collagen material and dermatomyositis/polymyositis.