Ng Y Y, Chow M P, Lyou J Y, Hu H Y, Yung C H, Fan C D, Huang T P
Division of Nephrology, Veterans General Hospital, Taipei, Taiwan, Republic of China.
Am J Kidney Dis. 1993 Feb;21(2):213-6. doi: 10.1016/s0272-6386(12)81097-3.
Because of inadequate renal synthesis of erythropoietin, the anemia associated with chronic renal failure has been treated successfully in most patients on hemodialysis with recombinant human erythropoietin. Hemolysis due to anti-Nform antibody in dialysis patients with the reused dialyzer may be one of the factors that cause refractoriness to erythropoietin therapy. Patients who do not respond to erythropoietin administration should be screened for anti-Nform antibody.
由于肾脏促红细胞生成素合成不足，大多数接受血液透析的慢性肾衰竭相关贫血患者使用重组人促红细胞生成素治疗已取得成功。复用透析器的透析患者中因抗N型抗体导致的溶血可能是促红细胞生成素治疗无效的因素之一。应对促红细胞生成素治疗无反应的患者进行抗N型抗体筛查。
