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回纹型风湿症。临床及血清补体研究。

Palindromic rheumatism. Clinical and serum complement study.

作者信息

Wajed M A, Brown D L, Currey H L

出版信息

Ann Rheum Dis. 1977 Feb;36(1):56-61. doi: 10.1136/ard.36.1.56.

DOI:10.1136/ard.36.1.56
PMID:843112
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1006630/
Abstract

A review of 39 patients diagnosed as suffering from palindromic rheumatism showed that 17 cases had evolved into typical rheumatoid arthritis (RA), while 22 had remained palindromic. The pattern of palindromic attacks in the two groups gave no grounds for regarding palindromic rheumatism as a separate condition from RA with palindromic onset. At the first attendance minor clinical or radiological changes, raised erythrocyte sedimentation rate, and positive serology were more common along those patients who were about to develop the picture of RA. Rheumatoid disease developing in patients with a palindromic onset was at least as severe as that among other patients with RA. 5 patients gave a history suggestive of fluid retention during the palindromic episodes, suggesting that attacks might be related to circulating immune complexes and altered vascular permeability. However, samples of blood obtained from 6 patients both during and between attacks showed no reduction in any of a variety of complement components tested.

摘要

对39例诊断为患有回纹型风湿症的患者进行的一项回顾显示,17例已发展为典型的类风湿性关节炎(RA),而22例仍为回纹型。两组回纹型发作的模式没有理由将回纹型风湿症视为与有回纹型起病的类风湿性关节炎不同的病症。首次就诊时,那些即将发展为类风湿性关节炎症状的患者中,轻微的临床或放射学改变、红细胞沉降率升高和血清学阳性更为常见。有回纹型起病的患者中发展出的类风湿性疾病至少与其他类风湿性关节炎患者中的一样严重。5例患者有在回纹型发作期间提示体液潴留的病史,这表明发作可能与循环免疫复合物和血管通透性改变有关。然而,在发作期间和发作之间从6例患者采集的血液样本显示,所检测的各种补体成分中没有任何一种减少。

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本文引用的文献

1
Palindromic rheumatism.复发性风湿症
Ann Rheum Dis. 1966 Jul;25(4):307-17. doi: 10.1136/ard.25.4.307.