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Colchicine toxicity: a multisystem disease.

作者信息

Naidus R M, Rodvien R, Mielke C H

出版信息

Arch Intern Med. 1977 Mar;137(3):394-6.

PMID:843157
Abstract

A 23-year-old black man survived a life-threatening multisystem disturbance resulting from a large single dose of colchicine administered intraurethrally for condyloma acuminata. Gastroenteritis and probable pancreatitis rapidly evolved into severe respiratory failure, marked neuromuscular problems, alopecia, and complete bone marrow aplasia. Within two months he had completely recovered. This patient demonstrates that colchicine should be used with extreme caution, if at all, for the therapy of condyloma acuminata.

摘要

相似文献

1
Colchicine toxicity: a multisystem disease.
Arch Intern Med. 1977 Mar;137(3):394-6.
2
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Topical treatment of penile condylomata acuminata with colchicine at 48-72 hours intervals.采用秋水仙碱每隔48至72小时对阴茎尖锐湿疣进行局部治疗。
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6
[Therapy of condyloma].[尖锐湿疣的治疗]
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7
Colchicine myoneuropathy in chronic renal failure patients with gout.慢性肾衰竭合并痛风患者的秋水仙碱性肌神经病
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Acute colchicine intoxication--possible role of erythromycin administration.急性秋水仙碱中毒——给予红霉素的可能作用。
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Colchicine-related death presenting as an unknown case of multiple organ failure.秋水仙碱相关死亡表现为不明原因的多器官功能衰竭病例。
J Emerg Med. 2005 May;28(4):445-8. doi: 10.1016/j.jemermed.2004.12.012.

引用本文的文献

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2
Electrooxidative tricyclic 6-7-6 fused-system domino assembly to allocolchicines by a removable radical strategy.通过可移除自由基策略实现电氧化三环 6-7-6 稠合体系多米诺组装合成别秋水仙碱
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Total Synthesis of (±)-Allocolchicine and Its Analogues Using Co-Catalyzed Alkyne [2 + 2 + 2]-Cyclotrimerization.使用共催化炔烃[2 + 2 + 2]环三聚反应全合成(±)-别秋水仙碱及其类似物
ACS Omega. 2017 Sep 8;2(9):5591-5600. doi: 10.1021/acsomega.7b00980. eCollection 2017 Sep 30.
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Curr Rheumatol Rep. 2008 Jul;10(3):218-27. doi: 10.1007/s11926-008-0036-3.
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Acute pancreatitis related to therapeutic dosing with colchicine: a case report.与秋水仙碱治疗剂量相关的急性胰腺炎:一例报告
J Med Case Rep. 2007 Aug 12;1:64. doi: 10.1186/1752-1947-1-64.
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Colchicine-induced rhabdomyolysis.秋水仙碱诱导的横纹肌溶解症。
Clin Rheumatol. 2007 Dec;26(12):2197-2199. doi: 10.1007/s10067-007-0682-2. Epub 2007 Jul 10.
8
Accidental colchicine poisoning in a dog.一只狗意外摄入秋水仙碱中毒。
Can Vet J. 2004 Jan;45(1):55-7.
9
Drug-induced pancreatitis.药物性胰腺炎
Drug Saf. 1996 Jun;14(6):406-23. doi: 10.2165/00002018-199614060-00006.
10
Colchicine cardiotoxicity following ingestion of Gloriosa superba tubers.摄入秋水仙后秋水仙碱的心脏毒性。 (注:Gloriosa superba tubers可能有误,推测应为Gloriosa superba,即秋水仙,是提取秋水仙碱的主要来源植物。)
Postgrad Med J. 1989 Oct;65(768):752-5. doi: 10.1136/pgmj.65.768.752.