Diengdoh J V, Shaw M D
Department of Neuropathology, Walton Centre for Neurology and Neurosurgery, Walton Hospital, Liverpool, United Kingdom.
Cancer. 1993 Feb 1;71(3):855-8. doi: 10.1002/1097-0142(19930201)71:3<855::aid-cncr2820710332>3.0.co;2-7.
The case of a left temporoparietal choroid plexus papilloma in a 12-year-old girl, which recurred 12 months after subtotal resection and apparent full recovery, is described.
The two consecutive surgical specimens were studied by light and electron microscopy.
The first surgical specimen showed a tumor composed of cells with distended cytoplasm packed with numerous mitochondria characteristic of "oncocytic" change. Thus, tumor was the rare benign oncocytic variant of choroid plexus papilloma. A repeat histologic study of the recurrent tumor 12 months later showed evidence of malignant evolution in the form of multinucleated cells with frequent, often bizarre, mitotic figures.
A rarely described oncocytic variant of choroid plexus papilloma that showed evidence of evolution from benign to malignant "oncocytoma" is discussed.
本文描述了一名12岁女孩左侧颞顶叶脉络丛乳头状瘤的病例，该肿瘤在次全切除并看似完全康复12个月后复发。
对连续的两份手术标本进行光镜和电镜研究。
第一份手术标本显示肿瘤由细胞质扩张的细胞组成，充满了大量具有“嗜酸性细胞”变化特征的线粒体。因此，该肿瘤是脉络丛乳头状瘤罕见的良性嗜酸性细胞变体。12个月后对复发性肿瘤进行的重复组织学研究显示，出现了恶性演变的证据，表现为多核细胞以及频繁出现的、通常形态怪异的有丝分裂图像。
本文讨论了一种罕见的脉络丛乳头状瘤嗜酸性细胞变体，该变体显示出从良性向恶性“嗜酸性细胞瘤”演变的证据。
