Titgemeyer F
Department of Biology, University of California, San Diego, La Jolla 92093-0116.
J Cell Biochem. 1993 Jan;51(1):69-74. doi: 10.1002/jcb.240510113.
Gram-negative bacteria are able to respond chemotactically to carbohydrates which are substrates of the bacterial phosphoenolpyruvate:sugar phosphotransferase system (PTS). The mechanism of signal transduction in PTS-mediated chemotaxis is different from the well-studied mechanism involving methyl-accepting chemotaxis proteins (MCPs). In PTS-mediated chemotaxis, carbohydrate transport is required, and phosphorylation seems to be involved in both excitation and adaptation. In this review the roles of the components of the PTS in chemotactic signal transduction are discussed.
糖磷酸转移酶系统(PTS)底物的碳水化合物产生趋化反应。PTS介导的趋化作用中的信号转导机制不同于涉及甲基接受趋化蛋白(MCPs)的已被充分研究的机制。在PTS介导的趋化作用中,需要碳水化合物转运,并且磷酸化似乎参与了兴奋和适应过程。在这篇综述中,讨论了PTS的各组分在趋化信号转导中的作用。