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β-链球菌所致的边缘性角膜溃疡

Marginal corneal ulcer due to beta-streptococcus.

作者信息

Kim H B, Ostler H B

出版信息

Arch Ophthalmol. 1977 Mar;95(3):454-5. doi: 10.1001/archopht.1977.04450030096012.

DOI:10.1001/archopht.1977.04450030096012
PMID:843277
Abstract

A 72-year-old woman with a low-grade nasolacrimal duct obstruction developed a hyperacute conjunctivitis caused by beta-hemolytic streptococci. This condition has been termed "conjunctivitis of Morax". An unusual feature consisting of a large, marginal furrow-like corneal ulcer was noted associated with a plastic iritis. The condition improved with the use of topical erythromycin, irrigation of the lacrimal sac with aqueous penicillin and oral penicillin. We believe that the marginal corneal ulcer was an actual infection of the corneal stroma resulting from the intense conjunctival chemosis trapping the exudate between the conjunctiva and the corneal epithelium, thus causing a breakdown of the corneal epithelium and allowing the organism to gain access to the stroma. Conjunctivitis of Morax can be clinically differentiated from a conjunctivitis associated with pneumococcal dacryocystitis and from the acute and hyperacute purulent conjunctivis due to infection with Neisseria.

摘要

一名72岁女性,患有低度鼻泪管阻塞,患上了由β溶血性链球菌引起的超急性结膜炎。这种病症被称为“莫拉克斯结膜炎”。注意到一个不寻常的特征,即伴有成形性虹膜炎的大的、边缘沟状角膜溃疡。使用局部红霉素、用青霉素水溶液冲洗泪囊以及口服青霉素后病情有所改善。我们认为边缘角膜溃疡是角膜基质的实际感染,这是由于强烈的结膜水肿将渗出物困在结膜和角膜上皮之间,从而导致角膜上皮破裂,使病原体得以进入基质。莫拉克斯结膜炎在临床上可与肺炎球菌性泪囊炎相关的结膜炎以及由奈瑟菌感染引起的急性和超急性脓性结膜炎相鉴别。

相似文献

1
Marginal corneal ulcer due to beta-streptococcus.β-链球菌所致的边缘性角膜溃疡
Arch Ophthalmol. 1977 Mar;95(3):454-5. doi: 10.1001/archopht.1977.04450030096012.
2
Marginal corneal ulcers with acute beta streptococcal conjunctivitis and chronic dacryocystitis.伴有急性β溶血性链球菌性结膜炎和慢性泪囊炎的边缘性角膜溃疡
Am J Ophthalmol. 1979 Apr;87(4):541-3. doi: 10.1016/0002-9394(79)90246-0.
3
Lacrimal conjunctivitis.
Bull Soc Belge Ophtalmol. 1990;238:61-9; discussion 69-70.
4
Ocular streptococcal infections.眼部链球菌感染
Cornea. 1988;7(4):295-9.
5
Neisserian conjunctivitis; treatment with penicillin.淋病性结膜炎;青霉素治疗
Calif Med. 1956 May;84(5):339-40.
6
Herellea vaginicola and ocular infections.阴道哈夫尼菌与眼部感染
Ann Ophthalmol. 1975 Nov;7(11):1485-8.
7
Bacteriology of the conjunctiva in pre-cataract surgery patients with occluded nasolacrimal ducts and the operation outcomes in Japanese patients.日本鼻泪管阻塞的白内障手术患者结膜的细菌学及手术结果
BMC Ophthalmol. 2017 Feb 20;17(1):15. doi: 10.1186/s12886-017-0410-x.
8
Aetiology and treatment of acute bacterial infection of the external eye.外眼急性细菌感染的病因及治疗
Br J Ophthalmol. 1982 Jun;66(6):357-60. doi: 10.1136/bjo.66.6.357.
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Streptococcus bovis causing perforating corneal ulcer.
Cornea. 2009 Jan;28(1):120-1. doi: 10.1097/ICO.0b013e3181822650.
10
Peripheral ulcerative keratitis triggered by bacterial conjunctivitis.由细菌性结膜炎引发的周边溃疡性角膜炎。
Nepal J Ophthalmol. 2010 Jan-Jun;2(1):71-3. doi: 10.3126/nepjoph.v2i1.3709.

引用本文的文献

1
Corneal ulcers with non-infectious appearance caused by nasolacrimal duct obstruction or canaliculitis.由鼻泪管阻塞或泪小管炎引起的具有非感染性外观的角膜溃疡。
Am J Ophthalmol Case Rep. 2022 Jul 9;27:101651. doi: 10.1016/j.ajoc.2022.101651. eCollection 2022 Sep.
2
Peripheral Ulcerative Keratitis: A Review.周边溃疡性角膜炎:综述
J Ophthalmic Vis Res. 2022 Apr 29;17(2):252-275. doi: 10.18502/jovr.v17i2.10797. eCollection 2022 Apr-Jun.
3
Aetiology and treatment of acute bacterial infection of the external eye.外眼急性细菌感染的病因及治疗
Br J Ophthalmol. 1982 Jun;66(6):357-60. doi: 10.1136/bjo.66.6.357.