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β-链球菌所致的边缘性角膜溃疡

Marginal corneal ulcer due to beta-streptococcus.

作者信息

Kim H B, Ostler H B

出版信息

Arch Ophthalmol. 1977 Mar;95(3):454-5. doi: 10.1001/archopht.1977.04450030096012.

Abstract

A 72-year-old woman with a low-grade nasolacrimal duct obstruction developed a hyperacute conjunctivitis caused by beta-hemolytic streptococci. This condition has been termed "conjunctivitis of Morax". An unusual feature consisting of a large, marginal furrow-like corneal ulcer was noted associated with a plastic iritis. The condition improved with the use of topical erythromycin, irrigation of the lacrimal sac with aqueous penicillin and oral penicillin. We believe that the marginal corneal ulcer was an actual infection of the corneal stroma resulting from the intense conjunctival chemosis trapping the exudate between the conjunctiva and the corneal epithelium, thus causing a breakdown of the corneal epithelium and allowing the organism to gain access to the stroma. Conjunctivitis of Morax can be clinically differentiated from a conjunctivitis associated with pneumococcal dacryocystitis and from the acute and hyperacute purulent conjunctivis due to infection with Neisseria.

摘要

一名72岁女性,患有低度鼻泪管阻塞,患上了由β溶血性链球菌引起的超急性结膜炎。这种病症被称为“莫拉克斯结膜炎”。注意到一个不寻常的特征,即伴有成形性虹膜炎的大的、边缘沟状角膜溃疡。使用局部红霉素、用青霉素水溶液冲洗泪囊以及口服青霉素后病情有所改善。我们认为边缘角膜溃疡是角膜基质的实际感染,这是由于强烈的结膜水肿将渗出物困在结膜和角膜上皮之间,从而导致角膜上皮破裂,使病原体得以进入基质。莫拉克斯结膜炎在临床上可与肺炎球菌性泪囊炎相关的结膜炎以及由奈瑟菌感染引起的急性和超急性脓性结膜炎相鉴别。

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