多沙普仑对绵羊胎儿呼吸的影响。
The effect of doxapram on fetal breathing in the sheep.
作者信息
Hogg M I, Golding R H, Rosen M
出版信息
Br J Obstet Gynaecol. 1977 Jan;84(1):48-50. doi: 10.1111/j.1471-0528.1977.tb12466.x.
Abstract
In five ewes of 105 to 120 days gestation intravenous doxapram (1.8 to 3.85 mg/kg) administered to the mother produced a dose-related increase in fetal breathing. This effect of doxapram might prove useful as a test of human fetal health. Fetal breathing movements could be a sensitive indication of the effects of drugs on the human fetal respiratory system.
摘要
在怀孕105至120天的五只母羊中，给母体静脉注射多沙普仑（1.8至3.85毫克/千克）会使胎儿呼吸出现剂量相关的增加。多沙普仑的这种作用可能被证明可作为检测人类胎儿健康的一种方法。胎儿呼吸运动可能是药物对人类胎儿呼吸系统影响的一个敏感指标。
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