Collinson P O, Moseley D, Stubbs P J, Carter G D
Department of Clinical Biochemistry, West Middlesex University Hospital, UK.
Ann Clin Biochem. 1993 Jan;30 ( Pt 1):11-6. doi: 10.1177/000456329303000102.
The diagnostic performance of a new enzyme linked immunosorbent assay for the cardiac structural protein troponin T in the differential diagnosis of ischaemic cardiac damage was assessed. A well documented set of patients admitted to the coronary care unit of a district general hospital were studied. At a cutoff value of 0.2 micrograms/L, troponin T measurements 12-24 h after admission or 12-16 to 24-48 h from onset of chest pain showed an overall efficiency of 97.6% for diagnosis of proven myocardial infarction. Troponin T was not detectable in patients when ischaemic heart disease could be excluded but was present in four patients with angina. Detectable troponin T in these angina patients was associated with subsequent cardiac events.
评估了一种用于心脏结构蛋白肌钙蛋白T的新型酶联免疫吸附测定法在缺血性心脏损伤鉴别诊断中的诊断性能。对一家地区综合医院冠心病监护病房收治的一组有充分记录的患者进行了研究。在入院后12 - 24小时或胸痛发作后12 - 16至24 - 48小时，肌钙蛋白T测量值的截断值为0.2微克/升时，对已证实的心肌梗死诊断的总体效率为97.6%。在可排除缺血性心脏病的患者中未检测到肌钙蛋白T，但在4例心绞痛患者中存在。这些心绞痛患者中可检测到的肌钙蛋白T与随后的心脏事件相关。
