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新生犬主动脉条的反应性

Reactivity of neonatal canine aortic strips.

作者信息

Gray S D

出版信息

Biol Neonate. 1977;31(1-2):10-4. doi: 10.1159/000240936.

DOI:10.1159/000240936
PMID:843545
Abstract

To determine whether vascular reactivity in the young animal is significantly different from that of the mature animal, helical strips of thoracic aorta were suspended in an organ bath of Krebs bicarbonate solution, and isometric tension was measured. The effects of norepinephrine, phenylphrine, tyramine, and KCl were studied. The neonatal vascular strips were less sensitive than adult strips to the adrenergic agents, but responsiveness to KCl was comparable in both groups.

摘要

为了确定幼龄动物的血管反应性是否与成年动物有显著差异,将胸主动脉螺旋条悬于 Krebs 碳酸氢盐溶液的器官浴槽中,测量等长张力。研究了去甲肾上腺素、去氧肾上腺素、酪胺和氯化钾的作用。新生动物的血管条对肾上腺素能药物的敏感性低于成年动物的血管条,但两组对氯化钾的反应性相当。

相似文献

1
Reactivity of neonatal canine aortic strips.新生犬主动脉条的反应性
Biol Neonate. 1977;31(1-2):10-4. doi: 10.1159/000240936.
2
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Contractile responses of spiral strips of large blood vessels from rabbits to transmural stimulation and tyramine.兔大血管螺旋条对跨壁刺激和酪胺的收缩反应。
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[Effects of angiotensin, norepinephrine and tyramine on rabbit aortic strips (author's transl)].血管紧张素、去甲肾上腺素和酪胺对兔主动脉条的作用(作者译)
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引用本文的文献

1
The effect of age on the responses of human isolated arteries to noradrenaline.年龄对人离体动脉对去甲肾上腺素反应的影响。
Br J Clin Pharmacol. 1982 Feb;13(2):237-9. doi: 10.1111/j.1365-2125.1982.tb01365.x.
2
Cellular mechanisms of impaired adrenergic responsiveness in neonatal dogs.新生犬肾上腺素能反应受损的细胞机制
J Clin Invest. 1981 Feb;67(2):319-27. doi: 10.1172/JCI110038.