Holý A
Ustav organické chemie a biochemie, CSAV, Praha.
Cas Lek Cesk. 1993 Jan 26;132(1):12-7.
This article reviews diverse strategies of rational development of antivirals based upon an interference with processes involved in viral multiplication cycle. With the aid of approved antiviral drugs as well as of antiviral drugs candidates in diverse stages of development this review demonstrates broad variability of chemical structure and mechanism of action in the field of antiviral development.
本文综述了基于干扰病毒增殖周期相关过程的抗病毒药物合理开发的多种策略。借助已获批的抗病毒药物以及处于不同开发阶段的抗病毒候选药物,本综述展示了抗病毒药物开发领域化学结构和作用机制的广泛多样性。