Prober C G
Department of Pediatrics, Stanford University School of Medicine, CA 94305.
Clin Obstet Gynecol. 1993 Mar;36(1):177-87. doi: 10.1097/00003081-199303000-00023.
Substantial advances have been made in our understanding of HSV and genital herpes. The molecular biology of viral structure and function and the pathogenesis of infection have been elucidated to a large degree, and epidemiologic investigations, based on reliable type-specific assays, have been done. Diagnostic techniques have been refined, and the value of therapy has been defined. Currently, management strategies for pregnant women and their neonates are based on data rather than hypothesis, and rational counseling is feasible. The next major advance in the field would be the availability of a safe and effective vaccine, the development and investigation of which is being pursued vigorously.
我们对单纯疱疹病毒(HSV)和生殖器疱疹的认识取得了重大进展。病毒结构与功能的分子生物学以及感染的发病机制在很大程度上已得到阐明,并且基于可靠的型特异性检测方法开展了流行病学调查。诊断技术得到了完善,治疗的价值也已明确。目前,针对孕妇及其新生儿的管理策略是基于数据而非假设,进行合理的咨询是可行的。该领域的下一个重大进展将是获得一种安全有效的疫苗,目前正在大力开展其研发和研究工作。