Belau L, Grävinghoff L, Keck E W
Kardiologische Abteilung, Universitäts-Krankenhaus Eppendorf, Hamburg.
Dtsch Med Wochenschr. 1993 Feb 12;118(6):169-75. doi: 10.1055/s-2008-1059314.
A persisting ductus arteriosus (PDA) was closed with the Rashkind occlusion system in 15 patients (12 children, aged 1.0 to 10.8 years, and three adults, aged 21, 33 and 56 years). The method consists of the implantation of a double umbrella of polyurethane foam mounted on platinum or steel wire introduced into the PDA via a transport catheter, the ductus being closed by thrombosing and epithelialization of the implant. The mean diameter of the PDA (as measured in the lateral aortogram) was 2.4 (1.4-5.3) mm. There were no complications of the procedure, nor any embolization or other serious complications. The PDA was completely occluded in eight patients, while a residual shunt remained in seven. In the oldest patient, aged 56 years, who had a residual shunt, increasing haemolysis required surgical closure of the ductus with a pericardial patch. These results indicate that, for patients weighing over 5 kg and with a ductus diameter of less than 10 mm, the closure method after Rashkind is a sparing and only slightly invasive procedure.
15例患者（12名儿童，年龄1.0至10.8岁，3名成人，年龄21、33和56岁）的动脉导管未闭（PDA）采用拉什金德封堵系统进行了封堵。该方法包括通过输送导管将安装在铂丝或钢丝上的聚氨酯泡沫双伞植入PDA，通过植入物的血栓形成和上皮化来封闭导管。PDA的平均直径（在侧位主动脉造影片上测量）为2.4（1.4 - 5.3）mm。该操作无并发症，也无栓塞或其他严重并发症。8例患者的PDA完全闭塞，7例仍有残余分流。在年龄最大的56岁患者中，存在残余分流，溶血加重，需要用心包补片进行手术封闭导管。这些结果表明，对于体重超过5kg且导管直径小于10mm的患者，拉什金德封堵法是一种微创且创伤较小的手术。
