Levy Y, Kornbrot B, Grunewald Z
Division of Pediatric Allergy/Immunology, Beilinson Medical Center, Petah Tikva.
Harefuah. 1993 Jan 1;124(1):18-20, 63.
Latex (natural rubber), which is obtained from the Hevea brasiliensis tree, is known to cause contact urticaria and aggravate pre-existing atopic dermatitis. We present a 4.5 year-old boy with bladder exstrophy and epispadias who developed generalized urticaria and bronchospasm during general anesthesia prior to correction of the epispadias. He had undergone previous urologic operations uneventfully. Allergic evaluation revealed atopy with specific IgE antibodies against latex. Immediate skin tests performed with the medications given during the general anesthesia were negative, supporting the possibility that his anaphylactic reaction was caused by exposure to latex during intubation and ventilation. Similar cases have recently been described, especially in children with congenital urogenital abnormalities who are frequently exposed to latex (catheters, surgical gloves). Exposure to latex in these children should be minimized. In addition, they should be prepared with orally administered corticosteroids and antihistamine medication prior to operation.
从巴西橡胶树中提取的天然橡胶乳胶，已知可引起接触性荨麻疹，并加重既往存在的特应性皮炎。我们报告一名4.5岁患有膀胱外翻和尿道上裂的男孩，在尿道上裂矫正术前全身麻醉期间出现全身性荨麻疹和支气管痉挛。他之前接受过泌尿外科手术，过程顺利。过敏评估显示对乳胶有特异性IgE抗体的特应性。对全身麻醉期间使用的药物进行的即时皮肤试验为阴性，这支持了他的过敏反应是由插管和通气过程中接触乳胶引起的可能性。最近已有类似病例报道，尤其是在经常接触乳胶（导管、手术手套）的先天性泌尿生殖系统异常儿童中。应尽量减少这些儿童接触乳胶的机会。此外，在手术前应为他们准备口服皮质类固醇和抗组胺药物。
